Description
Vibravet contains the broad spectrum antibiotic doxycycline, and advanced analogue of the tetracycline family. Doxycycline has a variety of features that make it extremely effective as a broad spectrum antibacterial agent in cats and dogs. Some key features of doxycycline are:
Absoption via the oral route is virtually complete and extremely rapid. As a result, serum levels of doxycycline reach concentrations comparable to those following intravenous administration and maintenance doses after the first day are much reduced.
Vibravet can be administered to patients with severe renal dysfunction because the primary route of excretion of doxycycline is through the enteric route.
Vibravet is highly lipophilic resulting in efficient tissue penetration.
Vibravet can be administered with food or milk without markedly impairing ist absorption.
Vibravet is effective against important pathogens which affect dogs and cats including Staphylococcus spp, Streptococcus spp, Escherichia coli, Pasteurella spp, Klebsiella spp, Proteus spp, Pseudomonas spp, Enterobacter spp, Actinobacter sps and Alcaligines spp, as well as Mycoplasma spp and Clamydia spp.
 
Indications:
Vibravet is indicated for the treatment of infections in dogs and cats caused by doxycycline- sensitive organisms including:
Skin, e.g pyoderma, folliculitis
gastrointestinal tract infections
Respiratory infections, e.g.  rhinitis, pharyngitis, bronchitis, pneumonia
Puerperal infections
Osteomyelitis
Otitis Media
Urogenital infections
 
Directions for Use
Do not use in pregnant bitches in the last 3 weeks of pregnancy and in new born animals during the first month of life.
The dose rate for cats and dogs is 5mg of doxycycline per kg bodyweight as a loading dose, then 2.5mg/kg every 12 hours for two doses then a maintenance dose 2.5mg/kg every 24hours/.
The recommendation should be made when dispensing doxycycline that it be administered either in conjunction with or immediately following feeding.